What is the purpose of the Prequel® prenatal test?

XXX (trisomy X)About X/Y chromosomal disorders

Two sex chromosomes (X and Y) determine whether a baby will be male or female. X and Y chromosomal disorders occur when  one copy of the sex chromosome is missing, has an extra copy, or is incomplete.

The Prequel test option with analysis of these chromosomes can be used for:

• XXX (trisomy X)
• XYY (Jacobs syndrome)
• XXY (Klinefelter syndrome)
• Monosomy of the X chromosome (T urner syndrome)

These disorders vary greatly in severity. Most affected individuals suffer from minor mental and behavioral disorders, as well as infertility.

Turner Syndrome

T urner syndrome is a genetic abnormality that affects only girls and occurs when one of the two X chromosomes is missing. T urner syndrome can cause a wide range of health and developmental abnormalities. These include short stature, lack of ovarian development, and heart defects.

Klinefelter Syndrome

La sindrome di Klinefelter è un'anomalia genetica in cui un bambino maschio ha una copia in più del cromosoma X, quindi il suo record genetico è 47, XXY. Le caratteristiche principali di questa sindrome sono l'infertilità e testicoli piccoli e mal funzionanti. Spesso i sintomi e i segni sono così impercettibili che persino i genitori e i bambini non sono consapevoli dell'esistenza dell'anomalia.